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Read further to learn more about hemorrhoids and Neosporin, and how they affect each other. What is Neosporin? Neosporin is a non prescription topical ointment that is made up of three kinds of antibiotics namely neomycin sulfate, .It does not seem like hemorrhoids are the problem. The skin around them does not usually peel and become inflammed like you are describing. I reccommend seeing .The only thing I can promise you about this cream is that you won't have a single regret from using it on your hemorrhoids. Question was Can i use neosporin for .Read further to learn more about hemorrhoids and Neosporin, and how they affect each other. Reference Natural reme.s for hemorrhoids Rory Maginnis Medium. Neosporin is a non prescription topical ointment that is made up of three kinds of antibiotics namely neomycin sulfate, polymyxin B sulfate and bacitracin zinc..Download Full Image